Candidate patient for treatment with continuous apomorphine infusion
*Correspondencia: Dr. Jaume Kulisevsky. Servicio de Neurología. Hospital de Sant Pau. Mas Casanovas, 90. E-08025 Barcelona.
Fax: +34 935 565 748.
E-mail: jkulisevsky@santpau.cat
Subcutaneous apomorphine infusion has been shown to be effective in reducing motor fluctuations and, to a lesser extent, also the levodopa induced dyskinesias in patients with advanced Parkinson's disease (PD). Based on the literature data, the following article reviews the clinical features of PD patients in order to be considered candidates for this therapy. In general, the vast majority of patients with advanced PD can benefit from this therapy and the authors' experience suggests that it should be considered as soon as the conventional pharmacological therapy fails to significantly reduce the number of daily off hours.